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Decoding efficacy and resistance space at a drug binding site.

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Title: Decoding efficacy and resistance space at a drug binding site.
Authors: Altmann S; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK., Mendoza-Martinez C; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK.; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, UK., Ridgway M; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK., Tinti M; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK., Saini JS; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK.; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, UK., Ibrahim PEGF; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK.; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, UK., Thomas M; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK.; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, UK., De Rycker M; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK.; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, UK., Bodkin MJ; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK.; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, UK., Horn D; Wellcome Centre for Anti-Infectives Research, Faculty of Life Sciences, University of Dundee, Dundee, UK. d.horn@dundee.ac.uk.
Source: Nature communications [Nat Commun] 2026 Feb 04; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-026-69187-5