Nrf2/HO-1-dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis.

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Title: Nrf2/HO-1-dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis.
Authors: Li D; The First College of Clinical Medicine, Shandong Traditional Chinese Medicine University, Jinan, Shandong, China., Xu F; Department of Proctology, Dongying People's Hospital, Dongying Hospital of Shandong Provincial Hospital Group, Dongying, Shandong, China., Wang W; Department of Gastroenterology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China., Jiang C; Department of Proctology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China., Cui W; Department of Proctology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China., Guan ZA; Department of Proctology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China., Gu C; Department of Proctology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 20; Vol. 16, pp. 1738408. Date of Electronic Publication: 2026 Jan 20 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1738408