Defining Safe and Effective Cefazolin Dosing Regimens for MSSA Infections in the CNS: Leveraging Sparse Real-World Data and PBPK Modeling.
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| Title: | Defining Safe and Effective Cefazolin Dosing Regimens for MSSA Infections in the CNS: Leveraging Sparse Real-World Data and PBPK Modeling. |
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| Authors: | Dubinsky S; Department of Critical Care, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada. sam.dubinsky@nshealth.ca., McIntyre M; Sinai Health-University Health Network Antimicrobial Stewardship Program, Mount Sinai Hospital, Toronto, ON, Canada.; University of Toronto Leslie Dan Faculty of Pharmacy, Toronto, ON, Canada., Kim MS; School of Pharmacy, University of Waterloo, Kitchener, ON, Canada., Hawryluk L; Critical Care Medicine, University of Toronto, Toronto, ON, Canada.; Medical Surgical/Neuroscience Intensive Care Unit, Toronto Western Hospital, Toronto, ON, Canada., Edginton A; School of Pharmacy, University of Waterloo, Kitchener, ON, Canada. |
| Source: | European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2026 Mar; Vol. 51 (2), pp. 193-204. Date of Electronic Publication: 2026 Feb 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2107-0180 |
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| DOI: | 10.1007/s13318-025-00981-0 |
