Programmable genome editing in human cells using RNA-guided bridge recombinases.
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| Title: | Programmable genome editing in human cells using RNA-guided bridge recombinases. |
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| Authors: | Pelea O; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Tálas A; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Carrera JF; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Mathis N; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., van de Venn L; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Yeh CD; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Kulcsár PI; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Marquart KF; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Weber Y; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Gerecke SE; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Harvey-Seutcheu IF; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Mailänder D; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Pfleiderer MM; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Chanez C; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Corn JE; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Schwank G; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Jinek M; Department of Biochemistry, University of Zurich, Zurich, Switzerland. |
| Source: | Science (New York, N.Y.) [Science] 2026 Mar 12; Vol. 391 (6790), pp. eadz1884. Date of Electronic Publication: 2026 Mar 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.adz1884 |
