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Programmable genome editing in human cells using RNA-guided bridge recombinases.

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Title: Programmable genome editing in human cells using RNA-guided bridge recombinases.
Authors: Pelea O; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Tálas A; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Carrera JF; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Mathis N; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., van de Venn L; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Yeh CD; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Kulcsár PI; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Marquart KF; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Weber Y; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Gerecke SE; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Harvey-Seutcheu IF; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Mailänder D; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Pfleiderer MM; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Chanez C; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Corn JE; Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Schwank G; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Jinek M; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Source: Science (New York, N.Y.) [Science] 2026 Mar 12; Vol. 391 (6790), pp. eadz1884. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Programmable genome editing in human cells using RNA-guided bridge recombinases.
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