View in EDS

NXTAGE: a phase 1/2 study of NXT007 to assess safety, pharmacokinetics, and efficacy in hemophilia A without inhibitors.

Saved in:
Bibliographic Details
Title: NXTAGE: a phase 1/2 study of NXT007 to assess safety, pharmacokinetics, and efficacy in hemophilia A without inhibitors.
Authors: Nogami K; Department of Pediatrics, Nara Medical University, Nara, Japan., You CW; Department of Pediatrics, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Republic of Korea., Park YS; Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea., Chen YC; Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan., Shen MC; Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan., Wang JD; Center for Rare Disease and Hemophilia, Taichung Veterans General Hospital, Taichung, Taiwan., Takeyama M; Division of Hemophilia, National Hospital Organization, Osaka National Hospital, Osaka, Japan., Amano K; Department of Laboratory Medicine, Tokyo Medical University, Tokyo, Japan., Chou SC; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Miwa T; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Chen CA; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Miyake T; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Iwasaki K; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Kobayashi R; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan., Shima M; Department of Pediatrics, Nara Medical University, Nara, Japan.; Thrombosis and Hemostasis Research Center, Nara Medical University, Nara, Japan.
Source: Blood [Blood] 2026 May 07; Vol. 147 (19), pp. 2261-2271.
Publication Type: Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41643195
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: NXTAGE: a phase 1/2 study of NXT007 to assess safety, pharmacokinetics, and efficacy in hemophilia A without inhibitors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Nogami+K%22">Nogami K</searchLink>; Department of Pediatrics, Nara Medical University, Nara, Japan.<br /><searchLink fieldCode="AU" term="%22You+CW%22">You CW</searchLink>; Department of Pediatrics, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+YS%22">Park YS</searchLink>; Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+MC%22">Shen MC</searchLink>; Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+JD%22">Wang JD</searchLink>; Center for Rare Disease and Hemophilia, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Takeyama+M%22">Takeyama M</searchLink>; Division of Hemophilia, National Hospital Organization, Osaka National Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Amano+K%22">Amano K</searchLink>; Department of Laboratory Medicine, Tokyo Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Chou+SC%22">Chou SC</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Miwa+T%22">Miwa T</searchLink>; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Chen+CA%22">Chen CA</searchLink>; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Miyake+T%22">Miyake T</searchLink>; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Iwasaki+K%22">Iwasaki K</searchLink>; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+R%22">Kobayashi R</searchLink>; Chugai Pharmaceutical Co, Ltd, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shima+M%22">Shima M</searchLink>; Department of Pediatrics, Nara Medical University, Nara, Japan.; Thrombosis and Hemostasis Research Center, Nara Medical University, Nara, Japan.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2026 May 07; Vol. 147 (19), pp. 2261-2271.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II; Multicenter Study
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603509 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0020 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200064971%22">00064971 </searchLink><i>NLM ISO Abbreviation: </i>Blood <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41643195
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1182/blood.2025031894
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2261
    Titles:
      – TitleFull: NXTAGE: a phase 1/2 study of NXT007 to assess safety, pharmacokinetics, and efficacy in hemophilia A without inhibitors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Nogami K
      – PersonEntity:
          Name:
            NameFull: You CW
      – PersonEntity:
          Name:
            NameFull: Park YS
      – PersonEntity:
          Name:
            NameFull: Chen YC
      – PersonEntity:
          Name:
            NameFull: Shen MC
      – PersonEntity:
          Name:
            NameFull: Wang JD
      – PersonEntity:
          Name:
            NameFull: Takeyama M
      – PersonEntity:
          Name:
            NameFull: Amano K
      – PersonEntity:
          Name:
            NameFull: Chou SC
      – PersonEntity:
          Name:
            NameFull: Miwa T
      – PersonEntity:
          Name:
            NameFull: Chen CA
      – PersonEntity:
          Name:
            NameFull: Miyake T
      – PersonEntity:
          Name:
            NameFull: Iwasaki K
      – PersonEntity:
          Name:
            NameFull: Kobayashi R
      – PersonEntity:
          Name:
            NameFull: Shima M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 07
              M: 05
              Text: 2026 May 07
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1528-0020
          Numbering:
            – Type: volume
              Value: 147
            – Type: issue
              Value: 19
          Titles:
            – TitleFull: Blood
              Type: main
ResultId 1