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Frailty in People with HIV Is Linked to Inflammation, Bone Health, and T-Cell Exhaustion.

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Title: Frailty in People with HIV Is Linked to Inflammation, Bone Health, and T-Cell Exhaustion.
Authors: Freeman ML; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Fitzgerald W; Section on Intercellular Interactions, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA., Clagett BM; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., O'Hare KA; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Jonnalagadda V; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Wilson BM; Geriatric Research, Education, and Clinical Center, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, Ohio, USA., Margolis L; Faculty of Natural Sciences and Medicine, Ilia State University, Tbilisi, Georgia., Wu K; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Tassiopoulos K; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Shive CL; Geriatric Research, Education, and Clinical Center, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, Ohio, USA.; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Erlandson KM; Division of Infectious Diseases, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Source: The Journal of infectious diseases [J Infect Dis] 2026 Jun 16; Vol. 233 (6), pp. 995-1004.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Freeman+ML%22">Freeman ML</searchLink>; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+W%22">Fitzgerald W</searchLink>; Section on Intercellular Interactions, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Clagett+BM%22">Clagett BM</searchLink>; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22O'Hare+KA%22">O'Hare KA</searchLink>; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Jonnalagadda+V%22">Jonnalagadda V</searchLink>; Rustbelt Center for AIDS Research, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+BM%22">Wilson BM</searchLink>; Geriatric Research, Education, and Clinical Center, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Margolis+L%22">Margolis L</searchLink>; Faculty of Natural Sciences and Medicine, Ilia State University, Tbilisi, Georgia.<br /><searchLink fieldCode="AU" term="%22Wu+K%22">Wu K</searchLink>; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Tassiopoulos+K%22">Tassiopoulos K</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shive+CL%22">Shive CL</searchLink>; Geriatric Research, Education, and Clinical Center, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, Ohio, USA.; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Erlandson+KM%22">Erlandson KM</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
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              Text: 2026 Jun 16
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