Fixed PEEP is not lung expansion physiology: reinterpreting the PROTHOR trial - Authors' reply.

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Title: Fixed PEEP is not lung expansion physiology: reinterpreting the PROTHOR trial - Authors' reply.
Authors: Wittenstein J; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany., Şentürk NM; Department of Anesthesiology, Istanbul Medical Faculty, Istanbul University, Istanbul, Türkiye; Department of Anesthesiology and Reanimation, School of Medicine, Acibadem University, Istanbul, Türkiye., Kiss T; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany; Department of Anesthesiology, Intensive-, Pain- and Palliative Care Medicine, Radebeul Hospital, Academic Hospital of the Technische Universität Dresden, Dresden, Germany., Schultz MJ; Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands., Serpa Neto A; Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia; Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, Melbourne, VIC, Australia; Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil., Gama de Abreu M; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany; Division of Intensive Care and Resuscitation, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA; Outcomes Research Consortium, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: mgabreu@aol.com.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2026 Feb; Vol. 14 (2), pp. e10.
Publication Type: Letter
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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ISSN:2213-2619
DOI:10.1016/S2213-2600(25)00460-6