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Fixed PEEP is not lung expansion physiology: reinterpreting the PROTHOR trial - Authors' reply.

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Title: Fixed PEEP is not lung expansion physiology: reinterpreting the PROTHOR trial - Authors' reply.
Authors: Wittenstein J; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany., Şentürk NM; Department of Anesthesiology, Istanbul Medical Faculty, Istanbul University, Istanbul, Türkiye; Department of Anesthesiology and Reanimation, School of Medicine, Acibadem University, Istanbul, Türkiye., Kiss T; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany; Department of Anesthesiology, Intensive-, Pain- and Palliative Care Medicine, Radebeul Hospital, Academic Hospital of the Technische Universität Dresden, Dresden, Germany., Schultz MJ; Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands., Serpa Neto A; Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia; Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, Melbourne, VIC, Australia; Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil., Gama de Abreu M; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany; Division of Intensive Care and Resuscitation, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA; Outcomes Research Consortium, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: mgabreu@aol.com.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2026 Feb; Vol. 14 (2), pp. e10.
Publication Type: Letter
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wittenstein+J%22">Wittenstein J</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany.<br /><searchLink fieldCode="AU" term="%22Şentürk+NM%22">Şentürk NM</searchLink>; Department of Anesthesiology, Istanbul Medical Faculty, Istanbul University, Istanbul, Türkiye; Department of Anesthesiology and Reanimation, School of Medicine, Acibadem University, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Kiss+T%22">Kiss T</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany; Department of Anesthesiology, Intensive-, Pain- and Palliative Care Medicine, Radebeul Hospital, Academic Hospital of the Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schultz+MJ%22">Schultz MJ</searchLink>; Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Serpa+Neto+A%22">Serpa Neto A</searchLink>; Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia; Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, Melbourne, VIC, Australia; Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Gama+de+Abreu+M%22">Gama de Abreu M</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden 01307, Germany; Division of Intensive Care and Resuscitation, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA; Outcomes Research Consortium, Department of Anesthesiology, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address: mgabreu@aol.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101605555 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-2619 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222132600%22">22132600 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Respir Med <i>Subsets: </i>MEDLINE; In Process
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              Text: 2026 Feb
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