An mRNA-delivered consensus allergen induces a neutralizing IgG response against food and pollen allergens.

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Title: An mRNA-delivered consensus allergen induces a neutralizing IgG response against food and pollen allergens.
Authors: Møiniche M; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Johansen KH; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Parrón-Ballesteros J; Department of Biochemistry and Molecular Biology, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain., Corneliussen JK; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Eriksen HH; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Voss LF; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Morillo B; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Furland UF; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Kringelum JV; SeeQ Diagnostics, Copenhagen, Denmark., Hadrup SR; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Luengo O; Department of Allergy, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Cardona V; Department of Allergy, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Bartra J; Department of Allergy, ICR, Hospital Clínic, University of Barcelona, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Immunology Department, CDB, Hospital Clinic, University of Barcelona, Barcelona, Spain., Pascal M; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Immunology Department, CDB, Hospital Clinic, University of Barcelona, Barcelona, Spain.; RETIC ARADyAL, RICORS de Enfermedades Inflamatorias REI (ISCIII), Madrid, Spain., Paris JL; Research Laboratory, IBIMA-Plataforma BIONAND, Málaga, Spain., Aranda CJ; Department of Biochemistry and Molecular Biology II, Instituto de Investigación Biosanitaria ibs.Granada, School of Pharmacy, University of Granada, Granada, Spain.; Institute of Nutrition and Food Technology 'José Mataix (INYTA)', Center of Biomedical Research, University of Granada, Granada, Spain., Turnay J; Department of Biochemistry and Molecular Biology, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain., Villalba M; Department of Biochemistry and Molecular Biology, Faculty of Chemistry, Complutense University of Madrid, Madrid, Spain., Münter R; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Mayorga C; Research Laboratory, IBIMA-Plataforma BIONAND, Málaga, Spain.; Allergy Unit, Regional University Hospital of Malaga, Málaga, Spain., Jenkins TP; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Laustsen AH; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. ahola@bio.dtu.dk., Rivera-de-Torre E; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. erdto@dtu.dk.
Source: Nature communications [Nat Commun] 2026 Feb 05; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-026-69134-4