Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route.
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| Title: | Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route. |
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| Authors: | Johnston SC; Virology Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Ginnetti AT; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Twenhafel NA; Pathology Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Norris SLW; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Chen S; Merck and Co., Inc., Rahway, New Jersey, United States of America., Moore JL; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Boyce CW; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Frick OM; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Dyer DN; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Marsh DJ; Merck and Co., Inc., Rahway, New Jersey, United States of America., Stevens SC; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Knapp WF; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Berrier KL; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Wan H; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Adam GC; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Hartingh TJ; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Esham HL; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Fiallos JO; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Blue EL; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Sifford WB; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Latty JD; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Mills HL; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Alli NA; Veterinary Medicine Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Piper AE; Virology Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Goodson AI; Research Program Office, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Meinig JM; Bacteriology Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Olsen DB; Merck and Co., Inc., West Point, Pennsylvania, United States of America., Lieberman LA; Merck and Co., Inc., Cambridge, Massachusetts, United States of America., Panchal RG; Molecular Biology Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America. |
| Source: | PloS one [PLoS One] 2026 Feb 06; Vol. 21 (2), pp. e0340118. Date of Electronic Publication: 2026 Feb 06 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0340118 |
