Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells.
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| Title: | Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells. |
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| Authors: | Tan YQ; Guangdong Provincial/Zhuhai Key Laboratory of IRADS & Programme of Food Science and Techonology, Beijing Normal-Hong Kong Baptist University, Zhuhai 519087, China., Shih CL; Clinical Research Center, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi City 60002, Taiwan., Chen YC; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan., Lee SH; School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan; Institute of Biopharmaceutical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan., Yang JR; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704302, Taiwan., Kuo CY; Institute of Oral Medicine and Materials, College of Medicine, Tzu Chi University, Hualien 97004, Taiwan., Chiou YS; Master Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807378, Taiwan. Electronic address: chiouyishiou@kmu.edu.tw. |
| Source: | Journal of hazardous materials [J Hazard Mater] 2026 Feb 15; Vol. 504, pp. 141290. Date of Electronic Publication: 2026 Jan 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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