PDE4 inhibitor rolipram dynamically regulates the balance between D1-MSNs and D2-MSNs in the DMS to modulate abnormal "Go" behavior associated with alcohol addiction.
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| Title: | PDE4 inhibitor rolipram dynamically regulates the balance between D1-MSNs and D2-MSNs in the DMS to modulate abnormal "Go" behavior associated with alcohol addiction. |
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| Authors: | Zhao W; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Zhao S; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Wang ZQ; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Chen XF; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Zong FJ; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China. zongfj@qdu.edu.cn., Zhang HT; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China. htzhang@ncu.edu.cn.; School of Pharmacy, Nanchang University, Nanchang, 330006, China. htzhang@ncu.edu.cn. |
| Source: | Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Jun; Vol. 47 (6), pp. 1501-1516. Date of Electronic Publication: 2026 Feb 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1745-7254 |
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| DOI: | 10.1038/s41401-025-01738-w |
