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PDE4 inhibitor rolipram dynamically regulates the balance between D1-MSNs and D2-MSNs in the DMS to modulate abnormal "Go" behavior associated with alcohol addiction.

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Title: PDE4 inhibitor rolipram dynamically regulates the balance between D1-MSNs and D2-MSNs in the DMS to modulate abnormal "Go" behavior associated with alcohol addiction.
Authors: Zhao W; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Zhao S; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Wang ZQ; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Chen XF; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China., Zong FJ; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China. zongfj@qdu.edu.cn., Zhang HT; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China. htzhang@ncu.edu.cn.; School of Pharmacy, Nanchang University, Nanchang, 330006, China. htzhang@ncu.edu.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Jun; Vol. 47 (6), pp. 1501-1516. Date of Electronic Publication: 2026 Feb 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Zhao+S%22">Zhao S</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Wang+ZQ%22">Wang ZQ</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Chen+XF%22">Chen XF</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Zong+FJ%22">Zong FJ</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China. zongfj@qdu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+HT%22">Zhang HT</searchLink>; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao, 266071, China. htzhang@ncu.edu.cn.; School of Pharmacy, Nanchang University, Nanchang, 330006, China. htzhang@ncu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2026 Jun; Vol. 47 (6), pp. 1501-1516. <i>Date of Electronic Publication: </i>2026 Feb 06.
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        Value: 10.1038/s41401-025-01738-w
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              Text: 2026 Jun
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