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Assessing residual allergenicity in heat-treated red lentil flours through simulated digestion, in vitro and in silico assays and peptidome approach.

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Title: Assessing residual allergenicity in heat-treated red lentil flours through simulated digestion, in vitro and in silico assays and peptidome approach.
Authors: Calcinai L; Department of Food and Drug, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy., Villa C; REQUIMTE-LAQV, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal., Cutroneo S; Department of Food and Drug, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy., Teixeira CSS; REQUIMTE-LAQV, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal., Prandi B; Department of Food and Drug, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy., Puxeddu I; Immuno-allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy., Ferreira IMPLVO; REQUIMTE-LAQV, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal., Mafra I; REQUIMTE-LAQV, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal., Costa J; REQUIMTE-LAQV, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address: jbcosta@ff.up.pt., Tedeschi T; Department of Food and Drug, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy. Electronic address: tullia.tedeschi@unipr.it.
Source: Food research international (Ottawa, Ont.) [Food Res Int] 2026 Mar 01; Vol. 227, pp. 118129. Date of Electronic Publication: 2025 Dec 24.
Publication Type: Journal Article
Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-7145
DOI:10.1016/j.foodres.2025.118129