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Radiotherapy enhances M1 macrophage immunogenic activity through IFNs induction and stimulation in TP53-wild type tumors.

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Title: Radiotherapy enhances M1 macrophage immunogenic activity through IFNs induction and stimulation in TP53-wild type tumors.
Authors: Cheng CC; Research Center of Radiation Medicine, Chang Gung University, Taoyuan, 333, Taiwan.; Division of Pulmonary Oncology and Interventional Bronchoscopy, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan., Yeh HZ; Division of Gastroenterology and Hepatology, Tungs' Taichung Metro Harbor Hospital, Taichung, 406, Taiwan., Sie ZL; Research Center of Radiation Medicine, Chang Gung University, Taoyuan, 333, Taiwan., Wang CL; Division of Pulmonary Oncology and Interventional Bronchoscopy, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan., Peng CL; Department of Isotope Application Research, National Atomic Research Institute, Taoyuan, 325, Taiwan., Ho AS; Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, 112, Taiwan., Wang CI; Department of Biochemistry, School of Medicine, China Medical University, Taichung, 400, Taiwan. ciwang@mail.cmu.edu.tw., Chang CC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, 110, Taiwan. chunchao@tmu.edu.tw.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. chunchao@tmu.edu.tw.; TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei, 110, Taiwan. chunchao@tmu.edu.tw.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Feb 07; Vol. 75 (3), pp. 71. Date of Electronic Publication: 2026 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Radiotherapy enhances M1 macrophage immunogenic activity through IFNs induction and stimulation in TP53-wild type tumors.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+CC%22">Cheng CC</searchLink>; Research Center of Radiation Medicine, Chang Gung University, Taoyuan, 333, Taiwan.; Division of Pulmonary Oncology and Interventional Bronchoscopy, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+HZ%22">Yeh HZ</searchLink>; Division of Gastroenterology and Hepatology, Tungs' Taichung Metro Harbor Hospital, Taichung, 406, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sie+ZL%22">Sie ZL</searchLink>; Research Center of Radiation Medicine, Chang Gung University, Taoyuan, 333, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CL%22">Wang CL</searchLink>; Division of Pulmonary Oncology and Interventional Bronchoscopy, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+CL%22">Peng CL</searchLink>; Department of Isotope Application Research, National Atomic Research Institute, Taoyuan, 325, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+AS%22">Ho AS</searchLink>; Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, 112, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CI%22">Wang CI</searchLink>; Department of Biochemistry, School of Medicine, China Medical University, Taichung, 400, Taiwan. ciwang@mail.cmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Chang+CC%22">Chang CC</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, 110, Taiwan. chunchao@tmu.edu.tw.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. chunchao@tmu.edu.tw.; TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei, 110, Taiwan. chunchao@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2026 Feb 07; Vol. 75 (3), pp. 71. <i>Date of Electronic Publication: </i>2026 Feb 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00262-026-04300-7
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      – Code: eng
        Text: English
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      – TitleFull: Radiotherapy enhances M1 macrophage immunogenic activity through IFNs induction and stimulation in TP53-wild type tumors.
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            – D: 07
              M: 02
              Text: 2026 Feb 07
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              Y: 2026
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