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Integrated study on anti-inflammatory and anti-atopic dermatitis efficacy of Saposhnikoviae Radix: UPLC-MS/GC-MS metabolomics and in vitro/in vivo experimental models.

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Title: Integrated study on anti-inflammatory and anti-atopic dermatitis efficacy of Saposhnikoviae Radix: UPLC-MS/GC-MS metabolomics and in vitro/in vivo experimental models.
Authors: Lu C; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Zhang XX; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Chen TT; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Ren SM; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Cheng HT; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Liu XQ; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Wang DM; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Xu XJ; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China. Electronic address: 17609809670@163.com., Pan YN; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China. Electronic address: panyingni@163.com.
Source: Fitoterapia [Fitoterapia] 2026 Apr; Vol. 190, pp. 107114. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-6971
DOI:10.1016/j.fitote.2026.107114