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Integrated study on anti-inflammatory and anti-atopic dermatitis efficacy of Saposhnikoviae Radix: UPLC-MS/GC-MS metabolomics and in vitro/in vivo experimental models.

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Title: Integrated study on anti-inflammatory and anti-atopic dermatitis efficacy of Saposhnikoviae Radix: UPLC-MS/GC-MS metabolomics and in vitro/in vivo experimental models.
Authors: Lu C; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Zhang XX; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Chen TT; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Ren SM; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Cheng HT; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Liu XQ; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Wang DM; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China., Xu XJ; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China. Electronic address: 17609809670@163.com., Pan YN; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China. Electronic address: panyingni@163.com.
Source: Fitoterapia [Fitoterapia] 2026 Apr; Vol. 190, pp. 107114. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated study on anti-inflammatory and anti-atopic dermatitis efficacy of Saposhnikoviae Radix: UPLC-MS/GC-MS metabolomics and in vitro/in vivo experimental models.
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  Data: <searchLink fieldCode="AU" term="%22Lu+C%22">Lu C</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+XX%22">Zhang XX</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+TT%22">Chen TT</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Ren+SM%22">Ren SM</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Cheng+HT%22">Cheng HT</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Liu+XQ%22">Liu XQ</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+DM%22">Wang DM</searchLink>; School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China.<br /><searchLink fieldCode="AU" term="%22Xu+XJ%22">Xu XJ</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China. Electronic address: 17609809670@163.com.<br /><searchLink fieldCode="AU" term="%22Pan+YN%22">Pan YN</searchLink>; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, PR China. Electronic address: panyingni@163.com.
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  Data: <searchLink fieldCode="JN" term="%2216930290R%22">Fitoterapia</searchLink> [Fitoterapia] 2026 Apr; Vol. 190, pp. 107114. <i>Date of Electronic Publication: </i>2026 Feb 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>16930290R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-6971 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220367326X%22">0367326X </searchLink><i>NLM ISO Abbreviation: </i>Fitoterapia <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.fitote.2026.107114
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              Text: 2026 Apr
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              Y: 2026
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