1‑(Phenylselanyl)-2‑(p‑tolyl)indolizine Mitigates Lipopolysaccharide (LPS)-Induced Depressive-Like Behavior by Modulating Oxidative Stress and Inflammatory Markers.
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| Title: | 1‑(Phenylselanyl)-2‑(p‑tolyl)indolizine Mitigates Lipopolysaccharide (LPS)-Induced Depressive-Like Behavior by Modulating Oxidative Stress and Inflammatory Markers. |
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| Authors: | da Rocha MJ; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Presa MH; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Nunes GD; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Barboza VS; Laboratory of Research in Biochemistry and Molecular Biology of Microorganisms, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Giongo JL; Laboratory of Research in Biochemistry and Molecular Biology of Microorganisms, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Vaucher RA; Laboratory of Research in Biochemistry and Molecular Biology of Microorganisms, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Pedra NS; Biomarker Laboratory, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Spanevello RM; Biomarker Laboratory, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Stefanello FM; Biomarker Laboratory, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Gomes CS; Clean Organic Synthesis Laboratory (LASOL), Graduate Program in Chemistry (PPGQ), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Lenardão EJ; Clean Organic Synthesis Laboratory (LASOL), Graduate Program in Chemistry (PPGQ), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Penteado F; Department of Chemistry, Federal University of Santa Maria - UFSM, Av Roraima, Building 18, Santa Maria, RS 97105-900, Brazil., Bortolatto CF; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil., Brüning CA; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil. |
| Source: | ACS omega [ACS Omega] 2026 Jan 20; Vol. 11 (4), pp. 6578-6590. Date of Electronic Publication: 2026 Jan 20 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41658132 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: 1‑(Phenylselanyl)-2‑(p‑tolyl)indolizine Mitigates Lipopolysaccharide (LPS)-Induced Depressive-Like Behavior by Modulating Oxidative Stress and Inflammatory Markers. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22da+Rocha+MJ%22">da Rocha MJ</searchLink>; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Presa+MH%22">Presa MH</searchLink>; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Nunes+GD%22">Nunes GD</searchLink>; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Barboza+VS%22">Barboza VS</searchLink>; Laboratory of Research in Biochemistry and Molecular Biology of Microorganisms, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Giongo+JL%22">Giongo JL</searchLink>; Laboratory of Research in Biochemistry and Molecular Biology of Microorganisms, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Vaucher+RA%22">Vaucher RA</searchLink>; Laboratory of Research in Biochemistry and Molecular Biology of Microorganisms, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Pedra+NS%22">Pedra NS</searchLink>; Biomarker Laboratory, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Spanevello+RM%22">Spanevello RM</searchLink>; Biomarker Laboratory, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Stefanello+FM%22">Stefanello FM</searchLink>; Biomarker Laboratory, Graduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Gomes+CS%22">Gomes CS</searchLink>; Clean Organic Synthesis Laboratory (LASOL), Graduate Program in Chemistry (PPGQ), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Lenardão+EJ%22">Lenardão EJ</searchLink>; Clean Organic Synthesis Laboratory (LASOL), Graduate Program in Chemistry (PPGQ), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Penteado+F%22">Penteado F</searchLink>; Department of Chemistry, Federal University of Santa Maria - UFSM, Av Roraima, Building 18, Santa Maria, RS 97105-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Bortolatto+CF%22">Bortolatto CF</searchLink>; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Brüning+CA%22">Brüning CA</searchLink>; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Chemical, Pharmaceutical and Food Sciences Center (CCQFA), Federal University of Pelotas (UFPel), P.O. Box 354, Pelotas, RS 96010-900, Brazil. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101691658%22">ACS omega</searchLink> [ACS Omega] 2026 Jan 20; Vol. 11 (4), pp. 6578-6590. <i>Date of Electronic Publication: </i>2026 Jan 20 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101691658 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2470-1343 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224701343%22">24701343 </searchLink><i>NLM ISO Abbreviation: </i>ACS Omega <i>Subsets: </i>PubMed not MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acsomega.5c11651 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 6578 Titles: – TitleFull: 1‑(Phenylselanyl)-2‑(p‑tolyl)indolizine Mitigates Lipopolysaccharide (LPS)-Induced Depressive-Like Behavior by Modulating Oxidative Stress and Inflammatory Markers. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: da Rocha MJ – PersonEntity: Name: NameFull: Presa MH – PersonEntity: Name: NameFull: Nunes GD – PersonEntity: Name: NameFull: Barboza VS – PersonEntity: Name: NameFull: Giongo JL – PersonEntity: Name: NameFull: Vaucher RA – PersonEntity: Name: NameFull: Pedra NS – PersonEntity: Name: NameFull: Spanevello RM – PersonEntity: Name: NameFull: Stefanello FM – PersonEntity: Name: NameFull: Gomes CS – PersonEntity: Name: NameFull: Lenardão EJ – PersonEntity: Name: NameFull: Penteado F – PersonEntity: Name: NameFull: Bortolatto CF – PersonEntity: Name: NameFull: Brüning CA IsPartOfRelationships: – BibEntity: Dates: – D: 20 M: 01 Text: 2026 Jan 20 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2470-1343 Numbering: – Type: volume Value: 11 – Type: issue Value: 4 Titles: – TitleFull: ACS omega Type: main |
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