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The TRIP12's intrinsically disordered region induces chromatin condensates and interferes with nuclear processes.

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Title: The TRIP12's intrinsically disordered region induces chromatin condensates and interferes with nuclear processes.
Authors: Vargas C; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Ricard A; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Varry D; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Muzzopappa F; Unité de Biologie Moléculaire, Cellulaire et du Développement. Centre de Biologie Intégrative, Université de Toulouse, CNRS, Toulouse, France., Brunet M; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France.; Institut des Maladies Métaboliques et Cardiovasculaires, Université de Toulouse, Inserm, Université Toulouse III-Paul Sabatier, Toulouse, France., Larrieu D; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Erdel F; Unité de Biologie Moléculaire, Cellulaire et du Développement. Centre de Biologie Intégrative, Université de Toulouse, CNRS, Toulouse, France., Labrousse G; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Hanoun N; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Ligat L; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Farcé M; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Bery N; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Cordelier P; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Dufresne M; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France., Torrisani J; University Toulouse, CNRS, INSERM, CRCT, Toulouse, France.
Source: IScience [iScience] 2026 Jan 02; Vol. 29 (2), pp. 114592. Date of Electronic Publication: 2026 Jan 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2589-0042
DOI:10.1016/j.isci.2025.114592