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Risk Factors for the Development of Food Allergy in Infants and Children: A Systematic Review and Meta-Analysis.

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Title: Risk Factors for the Development of Food Allergy in Infants and Children: A Systematic Review and Meta-Analysis.
Authors: Islam N; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Chu AWL; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Sheriff F; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada., Foroutan F; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Guyatt GH; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Brignardello-Petersen R; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Oykhman P; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Iorio A; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Izcovich A; Faculty of Medicine, Universidad del Salvador, Buenos Aires, Argentina., Morrison KM; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada., Roldan Benitez Y; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Couban RJ; Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada., Borovsky D; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Zhang Y; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Ologundudu L; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Pasumarthi K; Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Farooq SF; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Tong K; Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Tang WC; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Faisal H; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Khalid MF; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Asif MS; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., French S; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada., Waserman S; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Chinthrajah RS; Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Palo Alto, California., Sampson HA; Jaffe Food Allergy Institute, Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York., Mustafa SS; Department of Medicine, Rochester Regional Health, Rochester, New York.; Division of Allergy, Immunology, and Rheumatology, University of Rochester School of Medicine and Dentistry, Rochester, New York., Lieberman JA; Division of Pulmonology, Allergy and Immunology, Department of Pediatrics, The University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis., Järvinen KM; Center for Food Allergy, Division of Allergy and Immunology, Department of Pediatrics, University of Rochester Medical Center, Rochester, New York., Bailey S; Division of Pediatric Allergy and Immunology, Department of Pediatrics, Georgetown University, Washington, DC., Bégin P; Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada., Sicherer SH; Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, New York., Gerdts J; Food Allergy Canada, Toronto, Ontario, Canada., Carver M; The Asthma and Allergy Foundation of America, Arlington, Virginia., Mitchell L; Allergy and Asthma Network, Fairfax, Virginia., Cleary K; Food Allergy Research and Education, McLean, Virginia., Greenhawt MJ; Food Allergy Research and Education, McLean, Virginia., Wang J; Jaffe Food Allergy Institute, Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York., Anagnostou A; Division of Allergy and Immunology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas., Shaker MS; Department of Pediatrics and Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.; Section of Allergy and Immunology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire., Chandra-Puri A; Division of Community-Based Primary Care, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Fulkerson PC; US National Institute of Allergy and Infectious Diseases, Bethesda, Maryland., Wood RA; Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Madison., Chu DK; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.; The Research Institute of St Joe's Hamilton, St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.
Source: JAMA pediatrics [JAMA Pediatr] 2026 May 01; Vol. 180 (5), pp. 486-499.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589544 Publication Model: Print Cited Medium: Internet ISSN: 2168-6211 (Electronic) Linking ISSN: 21686203 NLM ISO Abbreviation: JAMA Pediatr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Risk Factors for the Development of Food Allergy in Infants and Children: A Systematic Review and Meta-Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Islam+N%22">Islam N</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chu+AWL%22">Chu AWL</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sheriff+F%22">Sheriff F</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Foroutan+F%22">Foroutan F</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Guyatt+GH%22">Guyatt GH</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Brignardello-Petersen+R%22">Brignardello-Petersen R</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Oykhman+P%22">Oykhman P</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Iorio+A%22">Iorio A</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Izcovich+A%22">Izcovich A</searchLink>; Faculty of Medicine, Universidad del Salvador, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Morrison+KM%22">Morrison KM</searchLink>; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Roldan+Benitez+Y%22">Roldan Benitez Y</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Couban+RJ%22">Couban RJ</searchLink>; Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Borovsky+D%22">Borovsky D</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ologundudu+L%22">Ologundudu L</searchLink>; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Pasumarthi+K%22">Pasumarthi K</searchLink>; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Farooq+SF%22">Farooq SF</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Tong+K%22">Tong K</searchLink>; Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Tang+WC%22">Tang WC</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Faisal+H%22">Faisal H</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Khalid+MF%22">Khalid MF</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Asif+MS%22">Asif MS</searchLink>; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22French+S%22">French S</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Waserman+S%22">Waserman S</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chinthrajah+RS%22">Chinthrajah RS</searchLink>; Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Palo Alto, California.<br /><searchLink fieldCode="AU" term="%22Sampson+HA%22">Sampson HA</searchLink>; Jaffe Food Allergy Institute, Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Mustafa+SS%22">Mustafa SS</searchLink>; Department of Medicine, Rochester Regional Health, Rochester, New York.; Division of Allergy, Immunology, and Rheumatology, University of Rochester School of Medicine and Dentistry, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Lieberman+JA%22">Lieberman JA</searchLink>; Division of Pulmonology, Allergy and Immunology, Department of Pediatrics, The University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis.<br /><searchLink fieldCode="AU" term="%22Järvinen+KM%22">Järvinen KM</searchLink>; Center for Food Allergy, Division of Allergy and Immunology, Department of Pediatrics, University of Rochester Medical Center, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Bailey+S%22">Bailey S</searchLink>; Division of Pediatric Allergy and Immunology, Department of Pediatrics, Georgetown University, Washington, DC.<br /><searchLink fieldCode="AU" term="%22Bégin+P%22">Bégin P</searchLink>; Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Sicherer+SH%22">Sicherer SH</searchLink>; Jaffe Food Allergy Institute, Serena and John Liew Division of Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Gerdts+J%22">Gerdts J</searchLink>; Food Allergy Canada, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Carver+M%22">Carver M</searchLink>; The Asthma and Allergy Foundation of America, Arlington, Virginia.<br /><searchLink fieldCode="AU" term="%22Mitchell+L%22">Mitchell L</searchLink>; Allergy and Asthma Network, Fairfax, Virginia.<br /><searchLink fieldCode="AU" term="%22Cleary+K%22">Cleary K</searchLink>; Food Allergy Research and Education, McLean, Virginia.<br /><searchLink fieldCode="AU" term="%22Greenhawt+MJ%22">Greenhawt MJ</searchLink>; Food Allergy Research and Education, McLean, Virginia.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Jaffe Food Allergy Institute, Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Anagnostou+A%22">Anagnostou A</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Shaker+MS%22">Shaker MS</searchLink>; Department of Pediatrics and Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.; Section of Allergy and Immunology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.<br /><searchLink fieldCode="AU" term="%22Chandra-Puri+A%22">Chandra-Puri A</searchLink>; Division of Community-Based Primary Care, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Fulkerson+PC%22">Fulkerson PC</searchLink>; US National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Wood+RA%22">Wood RA</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Madison.<br /><searchLink fieldCode="AU" term="%22Chu+DK%22">Chu DK</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.; The Research Institute of St Joe's Hamilton, St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.
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