Ultrarare Variants in DNA Damage Repair and Mitochondrial Genes in Pediatric Acute-Onset Neuropsychiatric Syndrome and Acute Behavioral Regression in Neurodevelopmental Disorders.

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Title: Ultrarare Variants in DNA Damage Repair and Mitochondrial Genes in Pediatric Acute-Onset Neuropsychiatric Syndrome and Acute Behavioral Regression in Neurodevelopmental Disorders.
Authors: Vettiatil D; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA., Soorajkumar A; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA., Dubin RA; Center for Epigenomics, Computational Genomics Core, Albert Einstein College of Medicine, Bronx, New York, USA., Pedrosa EM; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA., Schornagel A; Kinderpraktijk Zoetermeer, Zoetermeer, The Netherlands., Lambert JS; Infectious Diseases Department, Mater Misericordiae University Hospital, UCD School of Medicine, Dublin, Ireland., Costa IP; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA., McDonald J; Department of Pediatrics, Section of Pediatric Rheumatology, University of Chicago, Chicago, Illinois, USA., Swagemakers SMA; Department of Pathology and Clinical Bioinformatics, Erasmus MC, Rotterdam, The Netherlands., van der Spek PJ; Department of Pathology and Clinical Bioinformatics, Erasmus MC, Rotterdam, The Netherlands., Frankovich J; Department of Pediatrics, Division of Pediatric Allergy, Immunology, Rheumatology and Immune Behavioral Health Program, Stanford Children's Health and Stanford University School of Medicine, Palo Alto, California, USA., Cunningham JL; Department of Medical Sciences, Clinical Psychiatry, Uppsala University, Uppsala, Sweden., Lachman HM; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA, herb.lachman@einsteinmed.edu.; Departments of Genetics, and Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA, herb.lachman@einsteinmed.edu.
Source: Developmental neuroscience [Dev Neurosci] 2026 Feb 09, pp. 1-19. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 7809375 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9859 (Electronic) Linking ISSN: 03785866 NLM ISO Abbreviation: Dev Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1421-9859
DOI:10.1159/000550301