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Which trial do we need? Defining the optimal duration of antifungal therapy for invasive pulmonary aspergillosis.

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Title: Which trial do we need? Defining the optimal duration of antifungal therapy for invasive pulmonary aspergillosis.
Authors: Desoubeaux G; Tours University Hospital, Parasitology-Mycology-Tropical Medicine, Tours, France; University of Tours, INSERM UMR1100 Centre d'étude des pathologies respiratoires (CEPR), School of Medicine, Tours, France. Electronic address: guillaume.desoubeaux@univ-tours.fr., Mikulska M; Division of Infectious Diseases, University of Genova, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Lemaignen A; Tours University Hospital, Department of Infectious Diseases, Tours, France., Gyan E; Tours University Hospital, Haematology and Cell Therapy, Tours, France; University of Tours, INSERM U1069 Niche, Nutrition, Cancer & Metabolism Oxydatif (N2Cox), Tours, France., Stemler J; Division of Infectious Diseases, Department of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University Hospital Cologne, Cologne, Germany; Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine, University of Cologne, Cologne, Germany; Partner Site Bonn-Cologne, German Centre for Infection Research (DZIF), Cologne, Germany., Vanbiervliet Y; Department of Hematology, University Hospital Gasthuisberg, Leuven, Belgium; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium., Maertens J; Department of Hematology, University Hospital Gasthuisberg, Leuven, Belgium; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium., Lortholary O; Mycology Translational Research Group, Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Institut Pasteur, Université Paris Cité, Paris, France; Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Paccoud O; Mycology Translational Research Group, Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Institut Pasteur, Université Paris Cité, Paris, France; Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Slavin MA; Department of Infectious Diseases and National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Cornely OA; Division of Infectious Diseases, Department of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University Hospital Cologne, Cologne, Germany; Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine, University of Cologne, Cologne, Germany; Partner Site Bonn-Cologne, German Centre for Infection Research (DZIF), Cologne, Germany., Neofytos D; Service des Maladies Infectieuses, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Lanternier F; Mycology Translational Research Group, Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Institut Pasteur, Université Paris Cité, Paris, France; Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2026 May; Vol. 32 (5), pp. 683-686. Date of Electronic Publication: 2026 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE; In Process
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  Data: <searchLink fieldCode="AU" term="%22Desoubeaux+G%22">Desoubeaux G</searchLink>; Tours University Hospital, Parasitology-Mycology-Tropical Medicine, Tours, France; University of Tours, INSERM UMR1100 Centre d'étude des pathologies respiratoires (CEPR), School of Medicine, Tours, France. Electronic address: guillaume.desoubeaux@univ-tours.fr.<br /><searchLink fieldCode="AU" term="%22Mikulska+M%22">Mikulska M</searchLink>; Division of Infectious Diseases, University of Genova, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Lemaignen+A%22">Lemaignen A</searchLink>; Tours University Hospital, Department of Infectious Diseases, Tours, France.<br /><searchLink fieldCode="AU" term="%22Gyan+E%22">Gyan E</searchLink>; Tours University Hospital, Haematology and Cell Therapy, Tours, France; University of Tours, INSERM U1069 Niche, Nutrition, Cancer & Metabolism Oxydatif (N2Cox), Tours, France.<br /><searchLink fieldCode="AU" term="%22Stemler+J%22">Stemler J</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University Hospital Cologne, Cologne, Germany; Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine, University of Cologne, Cologne, Germany; Partner Site Bonn-Cologne, German Centre for Infection Research (DZIF), Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Vanbiervliet+Y%22">Vanbiervliet Y</searchLink>; Department of Hematology, University Hospital Gasthuisberg, Leuven, Belgium; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Maertens+J%22">Maertens J</searchLink>; Department of Hematology, University Hospital Gasthuisberg, Leuven, Belgium; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lortholary+O%22">Lortholary O</searchLink>; Mycology Translational Research Group, Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Institut Pasteur, Université Paris Cité, Paris, France; Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Paccoud+O%22">Paccoud O</searchLink>; Mycology Translational Research Group, Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Institut Pasteur, Université Paris Cité, Paris, France; Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Slavin+MA%22">Slavin MA</searchLink>; Department of Infectious Diseases and National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Cornely+OA%22">Cornely OA</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University Hospital Cologne, Cologne, Germany; Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine, University of Cologne, Cologne, Germany; Partner Site Bonn-Cologne, German Centre for Infection Research (DZIF), Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Neofytos+D%22">Neofytos D</searchLink>; Service des Maladies Infectieuses, Hôpitaux Universitaires de Genève, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lanternier+F%22">Lanternier F</searchLink>; Mycology Translational Research Group, Mycology Department, National Reference Center for Invasive Mycoses and Antifungals, Institut Pasteur, Université Paris Cité, Paris, France; Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
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