Low CD3+ and CD4+ T cell levels predict need for ventilatory support and in-hospital mortality in patients with COVID-19: a retrospective cohort study.

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Title: Low CD3+ and CD4+ T cell levels predict need for ventilatory support and in-hospital mortality in patients with COVID-19: a retrospective cohort study.
Authors: Martínez EL; Department of Internal Medicine, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain., Moreno-Pérez Ó; Department of Endocrinology and Nutrition, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain.; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain., Otero-Rodríguez S; Infectious Diseases Unit, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain., García-Sevila R; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain.; Department of Pneumology, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain., Marco-de-la-Calle F; Department of Immunology, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain., Sánchez-Martínez R; Department of Internal Medicine, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain.; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain., Merino-de-Lucas E; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain.; Infectious Diseases Unit, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain., Ramos-Rincón JM; Department of Internal Medicine, Alicante Institute for Health and Biomedical Research (ISABIAL), Dr. Balmis General University Hospital, Alicante, Spain.; Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain.
Source: Frontiers in medicine [Front Med (Lausanne)] 2026 Jan 26; Vol. 13, pp. 1740358. Date of Electronic Publication: 2026 Jan 26 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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