5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease status in patients with osteosarcoma.

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Title: 5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease status in patients with osteosarcoma.
Authors: Neczypor EW; Department of Medicine, The University of Chicago, Chicago, IL, USA., Reisert H; Albert Einstein College of Medicine, New York, NY, USA., Moore K; Department of Pediatrics, The University of Chicago, Chicago, IL, USA., Zeldin E; Albert Einstein College of Medicine, New York, NY, USA., Dubin RA; Computational Genomics Core, Albert Einstein College of Medicine, New York, NY, USA., Battle L; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., He C; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Hayashi M; Department of Pediatrics, University of Colorado Anschutz Medical Campus and Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA., Weiser DA; Albert Einstein College of Medicine, New York, NY, USA.; Department of Pediatrics, The Children's Hospital at Montefiore, New York, NY, USA., Applebaum MA; Department of Pediatrics, The University of Chicago, Chicago, IL, USA. mapplebaum@peds.bsd.uchicago.edu.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Feb 11; Vol. 10 (1). Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2397-768X
DOI:10.1038/s41698-026-01326-z