Divergent effects of topical deferoxamine treatment on skin and cancer cells uncovers its potential as a safe radioprotective agent in oncological applications.

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Title: Divergent effects of topical deferoxamine treatment on skin and cancer cells uncovers its potential as a safe radioprotective agent in oncological applications.
Authors: Ledwon JK; Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. jledwon@luriechildrens.org.; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA. jledwon@luriechildrens.org., Progri B; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA., Hallman T; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA., Reisner KR; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA., Figueroa AE; Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA., Bajaj A; Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Rai P; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA., Rodriguez GC; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA., Aronson S; Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Gosain AK; Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. argosain@luriechildrens.org.; Department of Plastic and Reconstructive Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Chicago, IL, USA. argosain@luriechildrens.org.
Source: Cancer cell international [Cancer Cell Int] 2026 Feb 11; Vol. 26 (1). Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139795 Publication Model: Electronic Cited Medium: Print ISSN: 1475-2867 (Print) Linking ISSN: 14752867 NLM ISO Abbreviation: Cancer Cell Int Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1475-2867
DOI:10.1186/s12935-026-04187-5