Tools and advanced imaging technologies for assessing intestinal epithelial barrier integrity: a systematic review.

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Title: Tools and advanced imaging technologies for assessing intestinal epithelial barrier integrity: a systematic review.
Authors: Vieujean S; Department of Gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Atreya R; Medical Department 1, University Hospital Erlangen, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany., Buda A; Gastroenterology Unit, Department of Gastrointestinal Oncological Surgery, S. Maria del Prato Hospital, Feltre, Italy., Caradec J; ThirtyFiveBio, Abingdon, United Kingdom., Citi S; Department of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland., Danese S; Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Milan, Italy., Dewit O; Department of Gastroenterology, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Friedrich M; Translational Gastroenterology and Liver Unit and NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Ghosh S; APC Microbiome Ireland, College of Medicine and Health, University College Cork, Cork, Ireland., Iacucci M; APC Microbiome Ireland, College of Medicine and Health, University College Cork, Cork, Ireland., Jairath V; Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Kaser A; Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, United Kingdom.; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Leong RW; Department of Gastroenterology, Macquarie University Hospital, Sydney, New South Wales, Australia., Neurath MF; MFN Department of Medicine 1, Ludwig Demling Center of Excellence in Endoscopy, Deutsches Zentrum Immuntherapie DZI, FAU University Erlangen-Nürnberg, Erlangen, Germany., Pierre N; Independent Researcher, Belgium., Pohin M; Immunoconcept UMR 5164 Immunology and immunogenetic Unit, CHU de Bordeaux, University of Bordeaux, Bordeaux, France., Rath T; University Hospital Erlangen, Department of Gastroenterology, Ludwig Demling Endoscopy Center, Erlangen, Germany., Rivière P; Service d'Hépato-gastroentérologie et oncologie digestive, CHU de Bordeaux. ImmunoConcept UMR5164, University of Bordeaux, Bordeaux, France., Travis S; Kennedy Institute of Rheumatology, Translational Gastroenterology and Liver Unit and NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Westcott J; ThirtyFiveBio, Abingdon, United Kingdom., Zeissig S; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Peyrin-Biroulet L; Department of Gastroenterology, CHRU Nancy, INSERM NGERE, Université de Lorraine, Vandœuvre-lès-Nancy, France.
Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2026 Apr 01; Vol. 330 (4), pp. G424-G458. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article; Systematic Review; Review
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1522-1547
DOI:10.1152/ajpgi.00447.2025