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Effect of in vitro synergy and additivity of vancomycin or daptomycin plus an antistaphylococcal β-lactam for methicillin-resistant Staphylococcus aureus bacteraemia on mortality: preplanned analysis from CAMERA2.

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Title: Effect of in vitro synergy and additivity of vancomycin or daptomycin plus an antistaphylococcal β-lactam for methicillin-resistant Staphylococcus aureus bacteraemia on mortality: preplanned analysis from CAMERA2.
Authors: Soo JZY; Division of Pharmacy, Singapore General Hospital, Singapore, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim TP; Division of Pharmacy, Singapore General Hospital, Singapore, Singapore; SingHealth Duke-NUS Pathology Academic Clinical Programme, Singapore, Singapore; SingHealth Duke-NUS Medicine Academic Clinical Programme, Singapore, Singapore., Ho JJY; Division of Pharmacy, Singapore General Hospital, Singapore, Singapore., Tong SYC; Victorian Infectious Disease Service, Royal Melbourne Hospital, and University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Lye DC; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; National Centre for Infectious Diseases, Singapore, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Davis JS; Department of Infectious Diseases, John Hunter Hospital, Newcastle, New South Wales, Australia; Menzies School of Health Research, Charles Darwin University, Casuarina, Northern Territory, Australia., Kwa ALH; Division of Pharmacy, Singapore General Hospital, Singapore, Singapore; SingHealth Duke-NUS Medicine Academic Clinical Programme, Singapore, Singapore; Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore, Singapore. Electronic address: andrea.kwa.l.h@sgh.com.sg.
Corporate Authors: Combination Antibiotics for MEthicillin Resistant Staphylococcus aureus (CAMERA2) Study Group
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2026 May; Vol. 32 (5), pp. 829-837. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1469-0691
DOI:10.1016/j.cmi.2026.01.032