Design and rationale of a multicenter paramedic randomized trial of noradrenaline versus adrenaline in the initial management of patients with cardiogenic shock-The PANDA trial.
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| Title: | Design and rationale of a multicenter paramedic randomized trial of noradrenaline versus adrenaline in the initial management of patients with cardiogenic shock-The PANDA trial. |
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| Authors: | Bloom JE; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Ball J; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Okyere D; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Voskoboinik A; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University., Dawson LP; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Nelson AJ; Royal Adelaide Hospital, Adelaide, South Australia, Australia., Percival M; Ambulance Victoria, Blackburn, Victoria, Australia., Meadley B; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Salathiel R; Ambulance Victoria, Blackburn, Victoria, Australia., McManamny T; Ambulance Victoria, Blackburn, Victoria, Australia; Department of Paramedicine, Monash University, Frankston, Victoria, Australia., Boggett S; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Batchelor R; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Hartshorne T; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University., Palmer S; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University., Reid C; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Curtin University, Bentley, Western Australia, Australia., Anderson D; Alfred Health, Melbourne, Victoria, Australia; Ambulance Victoria, Blackburn, Victoria, Australia., Pilcher D; Alfred Health, Melbourne, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Chew DP; Victorian Heart Hospital, Clayton, Victoria, Australia., Kaye DM; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University., Nehme Z; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Stub D; Alfred Health, Melbourne, Victoria, Australia; Monash Alfred Baker Centre for Cardiovascular Research, Monash University; Ambulance Victoria, Blackburn, Victoria, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. Electronic address: d.stub@alfred.org.au. |
| Corporate Authors: | PANDA Investigators |
| Source: | American heart journal [Am Heart J] 2026 Jul; Vol. 297, pp. 107378. Date of Electronic Publication: 2026 Feb 10. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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