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RIPK1 regulates β-cell fate via actions on gene expression and kinase signaling in a mouse model of β-cell self-reactivity.

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Title: RIPK1 regulates β-cell fate via actions on gene expression and kinase signaling in a mouse model of β-cell self-reactivity.
Authors: Contreras CJ; Department of Medicine, Roudebush VA Medical Center & Indiana University School of Medicine, Indianapolis, IN, USA.; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA., Mukherjee N; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA., Harris-Kawano A; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA., Mather EG; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA., Amarsaikhan N; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA., Davis C; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Berryhill CA; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Peyton M; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA., Kundu D; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA., Colglazier KA; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA., Miller AS; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA., Branco RCS; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Johnson TS; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA., Angus SP; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., You S; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Cai EP; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA., Templin AT; Department of Medicine, Roudebush VA Medical Center & Indiana University School of Medicine, Indianapolis, IN, USA. templin@iu.edu.; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA. templin@iu.edu.; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA. templin@iu.edu.; Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA. templin@iu.edu.
Source: Cell death & disease [Cell Death Dis] 2026 Feb 12; Vol. 17 (1), pp. 220. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: RIPK1 regulates β-cell fate via actions on gene expression and kinase signaling in a mouse model of β-cell self-reactivity.
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  Data: <searchLink fieldCode="AU" term="%22Contreras+CJ%22">Contreras CJ</searchLink>; Department of Medicine, Roudebush VA Medical Center & Indiana University School of Medicine, Indianapolis, IN, USA.; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+N%22">Mukherjee N</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Harris-Kawano+A%22">Harris-Kawano A</searchLink>; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Mather+EG%22">Mather EG</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Amarsaikhan+N%22">Amarsaikhan N</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Davis+C%22">Davis C</searchLink>; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Berryhill+CA%22">Berryhill CA</searchLink>; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Peyton+M%22">Peyton M</searchLink>; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Kundu+D%22">Kundu D</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Colglazier+KA%22">Colglazier KA</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Miller+AS%22">Miller AS</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Branco+RCS%22">Branco RCS</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+TS%22">Johnson TS</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Angus+SP%22">Angus SP</searchLink>; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22You+S%22">You S</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Cai+EP%22">Cai EP</searchLink>; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Templin+AT%22">Templin AT</searchLink>; Department of Medicine, Roudebush VA Medical Center & Indiana University School of Medicine, Indianapolis, IN, USA. templin@iu.edu.; Lilly Diabetes Center of Excellence, Indiana Biosciences Research Institute, Indianapolis, IN, USA. templin@iu.edu.; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA. templin@iu.edu.; Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA. templin@iu.edu.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Feb 12; Vol. 17 (1), pp. 220. <i>Date of Electronic Publication: </i>2026 Feb 12.
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