Human iPSC-based Modeling of Pulmonary Fibrosis Reveals p300/CBP Inhibition Suppresses Alveolar Transitional Cell State.

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Title: Human iPSC-based Modeling of Pulmonary Fibrosis Reveals p300/CBP Inhibition Suppresses Alveolar Transitional Cell State.
Authors: Tsutsui Y; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan., Masui A; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan., Konishi S; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan., Tsujimura T; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan., Iwasaki M; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan., Yamamoto T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Medical-risk Avoidance Based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto, Japan., Gotoh S; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan. gotoh.shimpei.5m@cira.kyoto-u.ac.jp.
Source: Nature communications [Nat Commun] 2026 Feb 12; Vol. 17 (1), pp. 1214. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-68909-z