Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis.

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Title: Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis.
Authors: Peng W; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Lin YY; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China., Lin AN; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Zheng YJ; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China., Cai XL; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Li YF; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Tang QY; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., He H; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Jan 28; Vol. 17, pp. 1733161. Date of Electronic Publication: 2026 Jan 28 (Print Publication: 2026).
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2026.1733161