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Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis.

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Title: Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis.
Authors: Peng W; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Lin YY; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China., Lin AN; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Zheng YJ; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China., Cai XL; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Li YF; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., Tang QY; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China., He H; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Jan 28; Vol. 17, pp. 1733161. Date of Electronic Publication: 2026 Jan 28 (Print Publication: 2026).
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Peng+W%22">Peng W</searchLink>; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Lin+YY%22">Lin YY</searchLink>; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Lin+AN%22">Lin AN</searchLink>; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zheng+YJ%22">Zheng YJ</searchLink>; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Cai+XL%22">Cai XL</searchLink>; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+YF%22">Li YF</searchLink>; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Tang+QY%22">Tang QY</searchLink>; Department of Respiratory and Critical Care Medicine, Guangdong Corps Hospital of People's Armed Police, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22He+H%22">He H</searchLink>; Department of Anesthesiology, General Hospital of Southern Theater Command, First Clinical College of Southern Medical University, Guangzhou, Guangdong, China.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 Jan 28; Vol. 17, pp. 1733161. <i>Date of Electronic Publication: </i>2026 Jan 28 (<i>Print Publication: </i>2026).
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        Value: 10.3389/fphar.2026.1733161
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        Text: English
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      – TitleFull: Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis.
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            – D: 28
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              Text: 2026 Jan 28
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              Y: 2026
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