Melatonin Mitigates Central Sensitization and Nociplastic Pain in Spinal Cord and Dorsal Root Ganglia of FM Rat Model: Modulation of SIRT1/PGC-1α/MAPK/NF-κB Signaling.
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| Title: | Melatonin Mitigates Central Sensitization and Nociplastic Pain in Spinal Cord and Dorsal Root Ganglia of FM Rat Model: Modulation of SIRT1/PGC-1α/MAPK/NF-κB Signaling. |
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| Authors: | Osama J; Postgraduate program in Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt.; Department of Pharmacology & Toxicology, Misr University for Science and Technology, Giza, Egypt., El-Gazar AA; Department of Pharmacology & Toxicology, October 6 University, Giza, Egypt., Ragab GM; Department of Pharmacology & Toxicology, Misr University for Science and Technology, Giza, Egypt., El-Sayed NS; Postgraduate program in Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt., Kamel AS; Postgraduate program in Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt. Ahmed.seifeldin@pharma.cu.edu.eg.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt. Ahmed.seifeldin@pharma.cu.edu.eg. |
| Source: | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2026 Feb 13; Vol. 21 (1), pp. 12. Date of Electronic Publication: 2026 Feb 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 101256586 Publication Model: Electronic Cited Medium: Internet ISSN: 1557-1904 (Electronic) Linking ISSN: 15571890 NLM ISO Abbreviation: J Neuroimmune Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41686296 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Melatonin Mitigates Central Sensitization and Nociplastic Pain in Spinal Cord and Dorsal Root Ganglia of FM Rat Model: Modulation of SIRT1/PGC-1α/MAPK/NF-κB Signaling. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Osama+J%22">Osama J</searchLink>; Postgraduate program in Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt.; Department of Pharmacology & Toxicology, Misr University for Science and Technology, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Gazar+AA%22">El-Gazar AA</searchLink>; Department of Pharmacology & Toxicology, October 6 University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Ragab+GM%22">Ragab GM</searchLink>; Department of Pharmacology & Toxicology, Misr University for Science and Technology, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Sayed+NS%22">El-Sayed NS</searchLink>; Postgraduate program in Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Kamel+AS%22">Kamel AS</searchLink>; Postgraduate program in Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt. Ahmed.seifeldin@pharma.cu.edu.eg.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Giza, Egypt. Ahmed.seifeldin@pharma.cu.edu.eg. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101256586%22">Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology</searchLink> [J Neuroimmune Pharmacol] 2026 Feb 13; Vol. 21 (1), pp. 12. <i>Date of Electronic Publication: </i>2026 Feb 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Science+%2B+Business+Media%22">Springer Science + Business Media </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101256586 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-1904 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215571890%22">15571890 </searchLink><i>NLM ISO Abbreviation: </i>J Neuroimmune Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41686296 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11481-025-10274-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 12 Titles: – TitleFull: Melatonin Mitigates Central Sensitization and Nociplastic Pain in Spinal Cord and Dorsal Root Ganglia of FM Rat Model: Modulation of SIRT1/PGC-1α/MAPK/NF-κB Signaling. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Osama J – PersonEntity: Name: NameFull: El-Gazar AA – PersonEntity: Name: NameFull: Ragab GM – PersonEntity: Name: NameFull: El-Sayed NS – PersonEntity: Name: NameFull: Kamel AS IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 02 Text: 2026 Feb 13 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1557-1904 Numbering: – Type: volume Value: 21 – Type: issue Value: 1 Titles: – TitleFull: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Type: main |
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