Synthetic lethality and DNA damage response targeting in cancer stem cells: a comprehensive review.

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Title: Synthetic lethality and DNA damage response targeting in cancer stem cells: a comprehensive review.
Authors: Sayed U; Faculty of Allied Medical Sciences, Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Amman, Jordan., Abdulsahib WK; Department of Pharmacology and Toxicology, College of Pharmacy, Al Farahidi University, Baghdad, Iraq. waleedk.abdulsahib@uoalfarahidi.edu.iq., Jasim IK; Department of Pharmaceutics, Faculty of Pharmacy, Al-Turath University, Baghdad, Iraq., Malathi H; Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India., Nayak PP; Department of Medical Oncology, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India., Alex Anand D; Department of Biomedical, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India., Mukherjee G; University Institute of Biotechnology, Chandigarh University, Mohali, Punjab, India., Sinha A; School of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India., Eshkaraev S; Department of Medicine, Termez University of Economics and Serviсe, Termez, Uzbekistan.
Source: Discover oncology [Discov Oncol] 2026 Feb 13; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101775142 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-6011 (Electronic) Linking ISSN: 27306011 NLM ISO Abbreviation: Discov Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2730-6011
DOI:10.1007/s12672-026-04587-z