Optimal control theory as a method for designing multidrug adaptive therapy regimens.

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Title: Optimal control theory as a method for designing multidrug adaptive therapy regimens.
Authors: Widdershins A; Penn State College of Medicine, Hershey, PA, USA., Hansen E; Huck Institutes of the Life Sciences, Pennsylvania State University, State College, PA, USA., Read A; Huck Institutes of the Life Sciences, Pennsylvania State University, State College, PA, USA., Hohl R; Penn State College of Medicine, Hershey, PA, USA. rhohl@pennstatehealth.psu.edu.
Source: NPJ systems biology and applications [NPJ Syst Biol Appl] 2026 Feb 14; Vol. 12 (1), pp. 27. Date of Electronic Publication: 2026 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-7189 (Electronic) Linking ISSN: 20567189 NLM ISO Abbreviation: NPJ Syst Biol Appl Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2056-7189
DOI:10.1038/s41540-025-00613-y