Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies.

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Title: Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies.
Authors: Xie W; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Fang J; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Wang Z; Department of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Li X; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Du J; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China. dujuan714@163.com., Ling C; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China. changquanling@smmu.edu.cn.
Source: Cancer gene therapy [Cancer Gene Ther] 2026 Mar; Vol. 33 (3), pp. 338-350. Date of Electronic Publication: 2026 Feb 14.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5500
DOI:10.1038/s41417-026-01007-w