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Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies.

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Title: Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies.
Authors: Xie W; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Fang J; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Wang Z; Department of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Li X; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China., Du J; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China. dujuan714@163.com., Ling C; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China. changquanling@smmu.edu.cn.
Source: Cancer gene therapy [Cancer Gene Ther] 2026 Mar; Vol. 33 (3), pp. 338-350. Date of Electronic Publication: 2026 Feb 14.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies.
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  Data: <searchLink fieldCode="AU" term="%22Xie+W%22">Xie W</searchLink>; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Fang+J%22">Fang J</searchLink>; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Du+J%22">Du J</searchLink>; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China. dujuan714@163.com.<br /><searchLink fieldCode="AU" term="%22Ling+C%22">Ling C</searchLink>; Department of traditional Chinese medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, China. changquanling@smmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229432230%22">Cancer gene therapy</searchLink> [Cancer Gene Ther] 2026 Mar; Vol. 33 (3), pp. 338-350. <i>Date of Electronic Publication: </i>2026 Feb 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9432230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5500 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209291903%22">09291903 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Gene Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41417-026-01007-w
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      – Code: eng
        Text: English
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      – TitleFull: Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies.
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              Text: 2026 Mar
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