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Exploring pathways leading to drug-resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus.

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Title: Exploring pathways leading to drug-resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus.
Authors: Hanin A; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France., Marois C; Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Neuro-Intensive Care Unit, Paris, France., Guillemaud M; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France., Chavez M; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France., Cosme L; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France., Hayatou Z; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France., Besnard A; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France., Goudard G; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France., Masson V; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France., Cousyn L; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France., Cheval M; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France., Denis JA; Sorbonne Université, Institut National de de la Santé et de Recherche Médicale (INSERM) UMR_S 938, Centre de Recherche Saint-Antoine, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Cellular and Molecular Oncobiology, Paris, France., Alkouri R; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France., Lamari F; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France., Bisulli F; IRCCS Istituto delle Scienze Neurologiche di Bologna, full member of the European Reference Network EpiCARE, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Eschbach K; Section of Neurology, Department of Pediatrics, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, Colorado, USA., Farias-Moeller R; Department of Neurology, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, USA., Gaspard N; Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Neurology, Hôpital Universitaire de Bruxelles-Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium., Gerard EE; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Giovannini G; Epilepsy Center and Neurophysiology Unit, Modena Academic Hospital, Modena, Italy., Gofton T; London Health Sciences Center, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Gopaul MT; Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, USA., Kellogg M; Oregon Health & Science University, Portland, Oregon, USA., Meletti S; Epilepsy Center and Neurophysiology Unit, Modena Academic Hospital, Modena, Italy.; Department of Biomedical, Metabolic, and Neural Sciences, UNIMORE, Modena, Italy., Muccioli L; IRCCS Istituto delle Scienze Neurologiche di Bologna, full member of the European Reference Network EpiCARE, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Pasini E; IRCCS Istituto delle Scienze Neurologiche di Bologna, full member of the European Reference Network EpiCARE, Bologna, Italy., Taraschenko O; Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA., Torcida N; Department of Neurology, Hôpital Universitaire de Bruxelles-Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium., Wainwright MS; Division of Pediatric Neurology, University of Washington, Seattle, WA, USA., Yoo JY; Icahn School of Medicine at Mount Sinai, New York, New York, USA., Wong N; NORSE Institute, Summit, New Jersey, USA., Bonnefont-Rousselot D; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France.; Université Paris Cité, UTCBS, Centre National de la Recherche Scientifique (CNRS), Institut National de de la Santé et de Recherche Médicale (INSERM), Paris, France., Demeret S; Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Neuro-Intensive Care Unit, Paris, France., Hirsch LJ; Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, USA., Navarro V; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.
Source: Epilepsia [Epilepsia] 2026 May; Vol. 67 (5), pp. 2326-2346. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Exploring pathways leading to drug-resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus.
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  Data: <searchLink fieldCode="AU" term="%22Hanin+A%22">Hanin A</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Marois+C%22">Marois C</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Neuro-Intensive Care Unit, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guillemaud+M%22">Guillemaud M</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chavez+M%22">Chavez M</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cosme+L%22">Cosme L</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hayatou+Z%22">Hayatou Z</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Besnard+A%22">Besnard A</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Goudard+G%22">Goudard G</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Masson+V%22">Masson V</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cousyn+L%22">Cousyn L</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cheval+M%22">Cheval M</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.<br /><searchLink fieldCode="AU" term="%22Denis+JA%22">Denis JA</searchLink>; Sorbonne Université, Institut National de de la Santé et de Recherche Médicale (INSERM) UMR_S 938, Centre de Recherche Saint-Antoine, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Cellular and Molecular Oncobiology, Paris, France.<br /><searchLink fieldCode="AU" term="%22Alkouri+R%22">Alkouri R</searchLink>; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lamari+F%22">Lamari F</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bisulli+F%22">Bisulli F</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, full member of the European Reference Network EpiCARE, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Eschbach+K%22">Eschbach K</searchLink>; Section of Neurology, Department of Pediatrics, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Farias-Moeller+R%22">Farias-Moeller R</searchLink>; Department of Neurology, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Gaspard+N%22">Gaspard N</searchLink>; Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Neurology, Hôpital Universitaire de Bruxelles-Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Gerard+EE%22">Gerard EE</searchLink>; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Giovannini+G%22">Giovannini G</searchLink>; Epilepsy Center and Neurophysiology Unit, Modena Academic Hospital, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Gofton+T%22">Gofton T</searchLink>; London Health Sciences Center, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Gopaul+MT%22">Gopaul MT</searchLink>; Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Kellogg+M%22">Kellogg M</searchLink>; Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Meletti+S%22">Meletti S</searchLink>; Epilepsy Center and Neurophysiology Unit, Modena Academic Hospital, Modena, Italy.; Department of Biomedical, Metabolic, and Neural Sciences, UNIMORE, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Muccioli+L%22">Muccioli L</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, full member of the European Reference Network EpiCARE, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Pasini+E%22">Pasini E</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, full member of the European Reference Network EpiCARE, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Taraschenko+O%22">Taraschenko O</searchLink>; Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Torcida+N%22">Torcida N</searchLink>; Department of Neurology, Hôpital Universitaire de Bruxelles-Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Wainwright+MS%22">Wainwright MS</searchLink>; Division of Pediatric Neurology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Yoo+JY%22">Yoo JY</searchLink>; Icahn School of Medicine at Mount Sinai, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Wong+N%22">Wong N</searchLink>; NORSE Institute, Summit, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Bonnefont-Rousselot+D%22">Bonnefont-Rousselot D</searchLink>; Department of Metabolic Biochemistry, DMU BioGeMH, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Pitié-Salpêtrière-Charles Foix University Hospital, Paris, France.; Université Paris Cité, UTCBS, Centre National de la Recherche Scientifique (CNRS), Institut National de de la Santé et de Recherche Médicale (INSERM), Paris, France.<br /><searchLink fieldCode="AU" term="%22Demeret+S%22">Demeret S</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Neuro-Intensive Care Unit, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hirsch+LJ%22">Hirsch LJ</searchLink>; Department of Neurology, Comprehensive Epilepsy Center, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Navarro+V%22">Navarro V</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Institut National de de la Santé et de Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche en Informatique et en Automatique (INRIA), Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié Salpêtrière, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Epilepsy Unit and Department of Clinical Neurophysiology, European Reference Network EpiCARE, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%222983306R%22">Epilepsia</searchLink> [Epilepsia] 2026 May; Vol. 67 (5), pp. 2326-2346. <i>Date of Electronic Publication: </i>2026 Feb 16.
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            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1528-1167
          Numbering:
            – Type: volume
              Value: 67
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Epilepsia
              Type: main
ResultId 1