View in EDS

PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation.

Saved in:
Bibliographic Details
Title: PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation.
Authors: Sverzhinsky A; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada., Xue H; Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, USA., Langelier MF; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada., Muniz Corrêa MV; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada., Del Mundo J; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Classen S; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Hammel M; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Rothenberg E; Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, USA., Pascal JM; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada. john.pascal@umontreal.ca.
Source: Nature communications [Nat Commun] 2026 Feb 16; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41698892
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Sverzhinsky+A%22">Sverzhinsky A</searchLink>; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Xue+H%22">Xue H</searchLink>; Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Langelier+MF%22">Langelier MF</searchLink>; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Muniz+Corrêa+MV%22">Muniz Corrêa MV</searchLink>; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Del+Mundo+J%22">Del Mundo J</searchLink>; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Classen+S%22">Classen S</searchLink>; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hammel+M%22">Hammel M</searchLink>; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rothenberg+E%22">Rothenberg E</searchLink>; Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pascal+JM%22">Pascal JM</searchLink>; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada. john.pascal@umontreal.ca.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Feb 16; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 16.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41698892
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-026-69375-3
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sverzhinsky A
      – PersonEntity:
          Name:
            NameFull: Xue H
      – PersonEntity:
          Name:
            NameFull: Langelier MF
      – PersonEntity:
          Name:
            NameFull: Muniz Corrêa MV
      – PersonEntity:
          Name:
            NameFull: Del Mundo J
      – PersonEntity:
          Name:
            NameFull: Classen S
      – PersonEntity:
          Name:
            NameFull: Hammel M
      – PersonEntity:
          Name:
            NameFull: Rothenberg E
      – PersonEntity:
          Name:
            NameFull: Pascal JM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 02
              Text: 2026 Feb 16
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1