View in EDS

Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines.

Saved in:
Bibliographic Details
Title: Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines.
Authors: Ravi Shankar AL; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany. abishek.laxmanan.ravi.shankar@item-extern.fraunhofer.de., Irwan J; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany., Spaenig M; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany., Carlier M; Amsterdam Institute for Life and Environment, Section Environment and Health, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands., Hansen T; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany., Zumbülte N; TZW: DVGW-Technologiezentrum Wasser (German Water Centre), Karlsruher Straße 84, 76139, Karlsruhe, Germany., Islam B; Certara Predictive Technologies, Sheffield, United Kingdom., Lundquist P; Department of Pharmacy, Uppsala University, Uppsala, Sweden., Svensson R; Department of Pharmacy, Uppsala University, Uppsala, Sweden., Gouin T; TG Environmental Research, Sharnbrook, United Kingdom., Hamers T; Amsterdam Institute for Life and Environment, Section Environment and Health, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands., Escher SE; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany.
Source: Archives of toxicology [Arch Toxicol] 2026 May; Vol. 100 (5), pp. 1877-1901. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41699307
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ravi+Shankar+AL%22">Ravi Shankar AL</searchLink>; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany. abishek.laxmanan.ravi.shankar@item-extern.fraunhofer.de.<br /><searchLink fieldCode="AU" term="%22Irwan+J%22">Irwan J</searchLink>; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Spaenig+M%22">Spaenig M</searchLink>; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Carlier+M%22">Carlier M</searchLink>; Amsterdam Institute for Life and Environment, Section Environment and Health, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hansen+T%22">Hansen T</searchLink>; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Zumbülte+N%22">Zumbülte N</searchLink>; TZW: DVGW-Technologiezentrum Wasser (German Water Centre), Karlsruher Straße 84, 76139, Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Islam+B%22">Islam B</searchLink>; Certara Predictive Technologies, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lundquist+P%22">Lundquist P</searchLink>; Department of Pharmacy, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Svensson+R%22">Svensson R</searchLink>; Department of Pharmacy, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Gouin+T%22">Gouin T</searchLink>; TG Environmental Research, Sharnbrook, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hamers+T%22">Hamers T</searchLink>; Amsterdam Institute for Life and Environment, Section Environment and Health, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Escher+SE%22">Escher SE</searchLink>; Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai- Fuchs-22 Strasse-1, 30625, Hannover, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220417615%22">Archives of toxicology</searchLink> [Arch Toxicol] 2026 May; Vol. 100 (5), pp. 1877-1901. <i>Date of Electronic Publication: </i>2026 Feb 17.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0417615 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0738 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203405761%22">03405761 </searchLink><i>NLM ISO Abbreviation: </i>Arch Toxicol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41699307
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00204-025-04268-w
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1877
    Titles:
      – TitleFull: Extrapolation of in vitro effect concentrations to in vivo bioavailable concentrations using PBK modelling in humans for two classes of persistent and mobile compounds: triazoles and triazines.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ravi Shankar AL
      – PersonEntity:
          Name:
            NameFull: Irwan J
      – PersonEntity:
          Name:
            NameFull: Spaenig M
      – PersonEntity:
          Name:
            NameFull: Carlier M
      – PersonEntity:
          Name:
            NameFull: Hansen T
      – PersonEntity:
          Name:
            NameFull: Zumbülte N
      – PersonEntity:
          Name:
            NameFull: Islam B
      – PersonEntity:
          Name:
            NameFull: Lundquist P
      – PersonEntity:
          Name:
            NameFull: Svensson R
      – PersonEntity:
          Name:
            NameFull: Gouin T
      – PersonEntity:
          Name:
            NameFull: Hamers T
      – PersonEntity:
          Name:
            NameFull: Escher SE
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1432-0738
          Numbering:
            – Type: volume
              Value: 100
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Archives of toxicology
              Type: main
ResultId 1