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Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus.

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Title: Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus.
Authors: Jones JC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Andreev K; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Sheth V; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Rowbotham K; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Vogel P; Department of Comparative Pathology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Patton CJ; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Seiler P; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Franks J; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Kandeil A; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt., Miller L; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Babu MM; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Webby RJ; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Govorkova EA; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Feb 18; Vol. 18 (837), pp. eadt3889. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus.
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  Data: <searchLink fieldCode="AU" term="%22Jones+JC%22">Jones JC</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Andreev+K%22">Andreev K</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Sheth+V%22">Sheth V</searchLink>; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Rowbotham+K%22">Rowbotham K</searchLink>; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Vogel+P%22">Vogel P</searchLink>; Department of Comparative Pathology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Patton+CJ%22">Patton CJ</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Seiler+P%22">Seiler P</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Franks+J%22">Franks J</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Kandeil+A%22">Kandeil A</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt.<br /><searchLink fieldCode="AU" term="%22Miller+L%22">Miller L</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Babu+MM%22">Babu MM</searchLink>; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Webby+RJ%22">Webby RJ</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.<br /><searchLink fieldCode="AU" term="%22Govorkova+EA%22">Govorkova EA</searchLink>; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Feb 18; Vol. 18 (837), pp. eadt3889. <i>Date of Electronic Publication: </i>2026 Feb 18.
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