View in EDS

Engineering a bifunctional cellobiose 2-epimerase into an isomerase capable of selective lactulose production.

Saved in:
Bibliographic Details
Title: Engineering a bifunctional cellobiose 2-epimerase into an isomerase capable of selective lactulose production.
Authors: Toplak A; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands. Electronic address: Ana.Toplak@fresenius-kabi.com., Wijma HJ; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), Faculty of Science and Engineering, University of Groningen, Nijenborgh 3, 9747 AG Groningen, the Netherlands., Janssen CJ; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands., Houben L; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands., Altay M; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands., Halmschlag BS; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands., Janssen DB; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), Faculty of Science and Engineering, University of Groningen, Nijenborgh 3, 9747 AG Groningen, the Netherlands., Cabri W; Department of Chemistry 'G. Ciamician', Alma Mater Studiorum, University of Bologna, Bologna 40126, Italy., Ricci A; Fresenius Kabi iPSUM, Via Roma 108, 20060, Cassina De Pecchi (MI), Italy. Electronic address: Antonio.Ricci@fresenius-kabi.com.
Source: Bioresource technology [Bioresour Technol] 2026 May; Vol. 447, pp. 134241. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41707773
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Engineering a bifunctional cellobiose 2-epimerase into an isomerase capable of selective lactulose production.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Toplak+A%22">Toplak A</searchLink>; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands. Electronic address: Ana.Toplak@fresenius-kabi.com.<br /><searchLink fieldCode="AU" term="%22Wijma+HJ%22">Wijma HJ</searchLink>; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), Faculty of Science and Engineering, University of Groningen, Nijenborgh 3, 9747 AG Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Janssen+CJ%22">Janssen CJ</searchLink>; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Houben+L%22">Houben L</searchLink>; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Altay+M%22">Altay M</searchLink>; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Halmschlag+BS%22">Halmschlag BS</searchLink>; Fresenius Kabi, I&D Center EnzyPep BV, Urmonderbaan 22, 6167 RD Geleen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Janssen+DB%22">Janssen DB</searchLink>; Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), Faculty of Science and Engineering, University of Groningen, Nijenborgh 3, 9747 AG Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cabri+W%22">Cabri W</searchLink>; Department of Chemistry 'G. Ciamician', Alma Mater Studiorum, University of Bologna, Bologna 40126, Italy.<br /><searchLink fieldCode="AU" term="%22Ricci+A%22">Ricci A</searchLink>; Fresenius Kabi iPSUM, Via Roma 108, 20060, Cassina De Pecchi (MI), Italy. Electronic address: Antonio.Ricci@fresenius-kabi.com.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229889523%22">Bioresource technology</searchLink> [Bioresour Technol] 2026 May; Vol. 447, pp. 134241. <i>Date of Electronic Publication: </i>2026 Feb 16.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Applied+Science%22">Elsevier Applied Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9889523 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2976 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209608524%22">09608524 </searchLink><i>NLM ISO Abbreviation: </i>Bioresour Technol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41707773
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.biortech.2026.134241
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 134241
    Titles:
      – TitleFull: Engineering a bifunctional cellobiose 2-epimerase into an isomerase capable of selective lactulose production.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Toplak A
      – PersonEntity:
          Name:
            NameFull: Wijma HJ
      – PersonEntity:
          Name:
            NameFull: Janssen CJ
      – PersonEntity:
          Name:
            NameFull: Houben L
      – PersonEntity:
          Name:
            NameFull: Altay M
      – PersonEntity:
          Name:
            NameFull: Halmschlag BS
      – PersonEntity:
          Name:
            NameFull: Janssen DB
      – PersonEntity:
          Name:
            NameFull: Cabri W
      – PersonEntity:
          Name:
            NameFull: Ricci A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1873-2976
          Numbering:
            – Type: volume
              Value: 447
          Titles:
            – TitleFull: Bioresource technology
              Type: main
ResultId 1