ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression.
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| Title: | ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression. |
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| Authors: | Xu ZH; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Chen J; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Laboratory Medicine, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China., He Y; Laboratory Animal Research Center, Xiamen University, Xiamen, Fujian, China., Lei C; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China., Wang XL; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Huang DF; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Li ZZ; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Zhou H; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Wang MY; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi, China., Song CG; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi, China., Lin J; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. linjuan2020@xmu.edu.cn., Liu W; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. w2liu@xmu.edu.cn.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. w2liu@xmu.edu.cn., Wu XN; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. xnwu@xmu.edu.cn.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. xnwu@xmu.edu.cn., Zhang WJ; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; Precision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; Ganzhou Key Laboratory of Immunotherapeutic Drugs Developing for Childhood Leukemia, Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Feb 18; Vol. 17 (1), pp. 228. Date of Electronic Publication: 2026 Feb 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-026-08499-2 |
