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ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression.

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Title: ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression.
Authors: Xu ZH; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Chen J; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Laboratory Medicine, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China., He Y; Laboratory Animal Research Center, Xiamen University, Xiamen, Fujian, China., Lei C; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China., Wang XL; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Huang DF; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Li ZZ; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China., Zhou H; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China., Wang MY; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi, China., Song CG; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi, China., Lin J; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. linjuan2020@xmu.edu.cn., Liu W; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. w2liu@xmu.edu.cn.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. w2liu@xmu.edu.cn., Wu XN; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. xnwu@xmu.edu.cn.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. xnwu@xmu.edu.cn., Zhang WJ; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; Precision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; Ganzhou Key Laboratory of Immunotherapeutic Drugs Developing for Childhood Leukemia, Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Feb 18; Vol. 17 (1), pp. 228. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression.
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  Data: <searchLink fieldCode="AU" term="%22Xu+ZH%22">Xu ZH</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; Department of Laboratory Medicine, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; Laboratory Animal Research Center, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Lei+C%22">Lei C</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Wang+XL%22">Wang XL</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Huang+DF%22">Huang DF</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Li+ZZ%22">Li ZZ</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Wang+MY%22">Wang MY</searchLink>; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Song+CG%22">Song CG</searchLink>; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; State Key Laboratory of Cellular Stress Biology, Cancer Research Center, School of Medicine, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. linjuan2020@xmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. w2liu@xmu.edu.cn.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. w2liu@xmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wu+XN%22">Wu XN</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. xnwu@xmu.edu.cn.; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China. xnwu@xmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+WJ%22">Zhang WJ</searchLink>; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; School of Medical Technology, Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; Precision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.; Ganzhou Key Laboratory of Immunotherapeutic Drugs Developing for Childhood Leukemia, Gannan Medical University, Ganzhou, Jiangxi, China. wjzhang_kyuu@gmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Feb 18; Vol. 17 (1), pp. 228. <i>Date of Electronic Publication: </i>2026 Feb 18.
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