CRISPR-Cas is beneficial in plasmid competition, but limited by competitor toxin-antitoxin activity when horizontally transferred.

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Title: CRISPR-Cas is beneficial in plasmid competition, but limited by competitor toxin-antitoxin activity when horizontally transferred.
Authors: Sünderhauf D; Environment and Sustainability Institute, University of Exeter, Penryn, United Kingdom., Ringger JR; Environment and Sustainability Institute, University of Exeter, Penryn, United Kingdom., Payne LJ; Section of Microbiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Pinilla-Redondo R; Section of Microbiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Gaze WH; European Centre for Environment and Human Health, University of Exeter, Penryn, United Kingdom., Brown SP; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America.; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, United States of America., van Houte S; Environment and Sustainability Institute, University of Exeter, Penryn, United Kingdom.
Source: PLoS biology [PLoS Biol] 2026 Feb 19; Vol. 24 (2), pp. e3003658. Date of Electronic Publication: 2026 Feb 19 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1545-7885
DOI:10.1371/journal.pbio.3003658