Genetic inhibition of IL-12β suppresses systolic overload-induced cardiac oxidative stress, inflammation, and heart failure development.
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| Title: | Genetic inhibition of IL-12β suppresses systolic overload-induced cardiac oxidative stress, inflammation, and heart failure development. |
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| Authors: | Bhattarai U; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Niu Z; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Pan L; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., He X; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Wang D; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Orman TC; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Wang H; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Zeng H; Department of Pharmacology and Toxicology, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Chen JX; Department of Pharmacology and Toxicology, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Xu X; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA, United States., Speed JS; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Clemmer JS; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Hall JE; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States., Chen Y; Department of Physiology and Biophysics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States. Electronic address: ychen2@umc.edu. |
| Source: | Redox biology [Redox Biol] 2026 Apr; Vol. 91, pp. 104082. Date of Electronic Publication: 2026 Feb 11. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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