Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence.
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| Title: | Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence. |
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| Authors: | Llop-Hernández À; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain., Verdura S; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain., López J; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, Girona, Spain., Martin-Castillo B; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; Unit of Clinical Research, Catalan Institute of Oncology, Girona, Spain., Menendez JA; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain. jmenendez@idibgi.org.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. jmenendez@idibgi.org., Cuyàs E; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain. ecuyas@idibgi.org.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. ecuyas@idibgi.org. |
| Source: | Cell death discovery [Cell Death Discov] 2026 Feb 19; Vol. 12 (1). Date of Electronic Publication: 2026 Feb 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-026-02967-6 |
