Trabectedin plus CD13-targeted tissue factor tTF-NGR against advanced relapsed or refractory soft tissue sarcoma: translational data, clinical safety and efficacy.
Saved in:
| Title: | Trabectedin plus CD13-targeted tissue factor tTF-NGR against advanced relapsed or refractory soft tissue sarcoma: translational data, clinical safety and efficacy. |
|---|---|
| Authors: | Hessling K; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Brand C; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Schwöppe C; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Gerwing M; Department of Radiology, University Hospital Muenster, Muenster, Germany., Pavelka S; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Berdel AF; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Hintelmann H; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Hamacher R; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany., Müller-Tidow C; Center for Internal Medicine 5, University Hospital Heidelberg, Heidelberg, Germany., Egerer G; Center for Internal Medicine 5, University Hospital Heidelberg, Heidelberg, Germany., Hartmann W; Gerhard-Domagk-Institute for Pathology, University Hospital Muenster, Muenster, Germany., Grünewald I; Gerhard-Domagk-Institute for Pathology, University Hospital Muenster, Muenster, Germany., Lindner LH; SarKUM, Department of Medicine III, Ludwig Maximilians University Hospital Großhadern, Munich, Germany., Di Gioia D; SarKUM, Department of Medicine III, Ludwig Maximilians University Hospital Großhadern, Munich, Germany., Hecker JS; Department of Medicine III, School of Medicine and Health and TranslaTUM Center for Translational Cancer Research, Technische Universitaet Muenchen, Munich, Germany., Maurer S; Department of Medicine III, School of Medicine and Health and TranslaTUM Center for Translational Cancer Research, Technische Universitaet Muenchen, Munich, Germany., Pink D; Department of Oncology and Palliative Care, HELIOS Klinikum Bad Saarow, Bad Saarow, Germany.; Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany., Fried M; University Cancer Center Mainz (UCT Mainz) and Clinic and Polyclinic for Internal Medicine III, University Hospital Mainz, Mainz, Germany., Zapata Bonilla SA; University Cancer Center Mainz (UCT Mainz) and Clinic and Polyclinic for Internal Medicine III, University Hospital Mainz, Mainz, Germany., Scheuble AM; Department of Medicine (Oncology, Gastroenterology, Hepatology, Pulmonology), University of Leipzig Medical Center, Comprehensive Cancer Center Central Germany (CCCG), Leipzig, Germany., Lordick F; Department of Medicine (Oncology, Gastroenterology, Hepatology, Pulmonology), University of Leipzig Medical Center, Comprehensive Cancer Center Central Germany (CCCG), Leipzig, Germany., Ivanyi P; Department of Hematology and Oncology, Medizinische Hochschule Hannover, Hannover, Germany., Fobker M; Central Laboratory, University Hospital Muenster, Muenster, Germany., Lenz G; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Gerss J; Institute of Biostatistics and Clinical Research, University of Muenster, Muenster, Germany., Kessler T; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany., Berdel WE; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany. berdel@uni-muenster.de., Schliemann C; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital of Muenster, Albert‑Schweitzer‑Campus 1, 48149, Muenster, Germany. Christoph.Schliemann@ukmuenster.de. |
| Source: | Scientific reports [Sci Rep] 2026 Feb 19; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2045-2322 |
|---|---|
| DOI: | 10.1038/s41598-026-40362-4 |
