Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens.
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| Title: | Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens. |
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| Authors: | Metz P; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.; Department of Neurosurgery, Erasmus University Medical Centre, Rotterdam, The Netherlands., Alves-Vasconcelos S; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Wallbank R; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Riepsaame J; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.; Genome Engineering Oxford, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Brown S; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Hassan AB; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK. bass.hassan@path.ox.ac.uk. |
| Source: | BMC genomics [BMC Genomics] 2026 Feb 20; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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